Error 0x80040421

Value: -2147220447 | 0x80040421 | 2147746849

What does it mean ?

DS_E_ALREADYDISABLED  
The content index is already disabled.
Value: 1057 | 0x0421 | 0b0000010000100001

Where does it come from ?

FACILITY_ITF  
COM/OLE Interface management. FACILITY_ITF is designated for user-defined error codes returned from interface methods
Value: 4 | 0x004 | 0b00000100

Other Errors for FACILITY_ITF