Error 0x80042548

Value: -2147211960 | 0x80042548 | 2147755336

What does it mean ?

VDS_E_PLEX_LAST_ACTIVE  
The last healthy plex cannot be removed.
Value: 9544 | 0x2548 | 0b0010010101001000

Where does it come from ?

FACILITY_ITF  
COM/OLE Interface management. FACILITY_ITF is designated for user-defined error codes returned from interface methods
Value: 4 | 0x004 | 0b00000100

Other Errors for FACILITY_ITF