Error 0x80045073

Value: -2147200909 | 0x80045073 | 2147766387

What does it mean ?

SPERR_SECMGR_CHANGE_NOT_ALLOWED  
When there is a cfg grammar loaded, we don't allow changing the security manager
Value: 20595 | 0x5073 | 0b0101000001110011

Where does it come from ?

FACILITY_ITF  
COM/OLE Interface management. FACILITY_ITF is designated for user-defined error codes returned from interface methods
Value: 4 | 0x004 | 0b00000100

Other Errors for FACILITY_ITF