Error 0x80501003

Value: -2142236669 | 0x80501003 | 2152730627

What does it mean ?

ERROR_MP_ACTIVE_THREATS  
Value: 4099 | 0x1003 | 0b0001000000000011

Where does it come from ?

FACILITY_WINDOWS_DEFENDER  
Windows Defender
Value: 80 | 0x050 | 0b01010000

Other Errors for FACILITY_WINDOWS_DEFENDER